Darzalex (daratumumab)
Patient Assistance Program Guide — Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)
Do You Qualify?
Income
Up to $45,180 for a single person
Insurance
Must be uninsured, have no coverage for the requested medication, or be a Medicare patient who meets specific criteria and has been denied or cannot afford their cost-share.
Residency
Must live in the United States or a U.S. Territory and be treated by a U.S. licensed healthcare provider.
Income Limits (300% FPL)
Calculated at 300% FPL; higher thresholds may apply for specific oncology medications or cases of financial hardship as determined by the foundation.
Based on 2025 HHS Federal Poverty Level guidelines.
# A Patient Guide to Getting Darzalex Through the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)
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Who Qualifies for the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)?
If you need Darzalex (daratumumab) but cannot afford it, you may be able to get it at no cost through the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF). This program is designed to help patients who lack the insurance coverage or financial means to pay for this medication.
To qualify, your annual income generally must be at or below $45,180 if you live alone, with higher limits for larger households. You must also meet specific insurance requirements — in most cases, you need to be uninsured, have no coverage for Darzalex specifically, or be a Medicare patient who has been denied coverage or cannot afford your cost-share. If you meet these criteria, the JJPAF may be able to provide Darzalex to you at no charge.
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About Darzalex (daratumumab)
Darzalex (daratumumab) is a prescription medication made by Janssen, a pharmaceutical company of Johnson & Johnson. It is FDA-approved to treat multiple myeloma and AL amyloidosis, two serious blood-related conditions. Darzalex belongs to a class of drugs called CD38-directed monoclonal antibodies, meaning it targets a specific protein found on certain abnormal cells.
Without insurance, Darzalex can cost tens of thousands of dollars per treatment cycle, making it out of reach for many patients. Because no FDA-approved biosimilar versions are currently available, there is no lower-cost generic alternative on the market. This is exactly the kind of situation patient assistance programs are built to address.
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Income Eligibility: Full Breakdown
The JJPAF uses federal poverty level (FPL) guidelines to determine income eligibility. The table below shows the general maximum annual income allowed based on your household size:
| Household Size | Max Annual Income |
|---|---|
| 1 person | $45,180 |
| 2 persons | $61,320 |
| 3 persons | $77,460 |
| 4 persons | $93,600 |
These limits are calculated at 300% of the federal poverty level. If your household has more than four people, the income threshold will continue to increase for each additional person.
Income is typically verified using your most recent U.S. Income Tax Return (Form 1040 or 1040-SR). If you did not file a tax return, you may submit W-2 or 1099 forms, or your last two pay stubs if no tax return is available.
If your income is above these limits, do not assume you are automatically disqualified. The foundation notes that higher income thresholds may apply for certain oncology medications or in cases of documented financial hardship. It is worth calling (800) 652-6227 to ask whether an exception may apply to your situation before giving up on applying.
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Insurance Requirements Explained
Your insurance situation plays a major role in whether you qualify. Here is how different coverage scenarios are handled:
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Step-by-Step: How to Apply
Follow these steps to apply for Darzalex through the JJPAF:
1. Gather your documents. You will need: your most recent U.S. Income Tax Return (Form 1040 or 1040-SR), or W-2, 1099 forms, or your last two pay stubs if no tax return is available. You will also need a valid prescription for Darzalex from your healthcare provider.
2. Complete the application. The application requires signatures from both you and your healthcare provider. You can start or download the application at https://www.jjpaf.org/. If you need help completing it, call (800) 652-6227 for assistance.
3. Submit your application. You have multiple ways to submit:
- Online: Visit https://www.jjpaf.org/ to apply or upload documents electronically.
- By phone: Call (800) 652-6227 to speak with a program representative.
- By fax: Send your completed application and supporting documents to (888) 526-5168.
4. Wait for confirmation. Once the JJPAF receives your complete application, a decision is typically made within 2 to 3 business days.
5. Your prescriber is notified. If approved, the program will communicate directly with your healthcare provider's office regarding next steps and medication shipment.
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What to Expect: Timeline and Delivery
After submitting a complete application, most patients receive a decision within 2 to 3 business days. Incomplete applications may take longer, so double-check that all required documents are included before submitting.
If approved, Darzalex is shipped directly to your prescriber's office, not to your home. You do not need to pick it up at a pharmacy. Your healthcare provider's office will let you know when the medication has arrived and schedule your treatment accordingly.
Approval through the JJPAF is not permanent. You will need to reapply once per year to continue receiving assistance. Your care team or the program may send a reminder when reauthorization is due, but it is a good idea to track your approval date and plan ahead.
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Alternatives If You Don't Qualify
If you do not meet the JJPAF eligibility requirements, there are other options to explore:
1. Biosimilars: There are currently no FDA-approved biosimilars for Darzalex, so a lower-cost alternative in this category is not yet available.
2. Manufacturer savings card: If you have private insurance that covers Darzalex, you may be eligible for a savings card through Janssen that reduces your out-of-pocket costs. Visit https://www.darzalex.com/darzalex-faspro/savings-support to learn more and check eligibility.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own programs to help residents pay for medications. Eligibility and benefits vary by state. Contact your state's department of health or aging to ask what programs may be available to you.
4. NeedyMeds.org: This free, nonprofit database lists hundreds of patient assistance programs, copay cards, and other drug cost resources. Visit NeedyMeds.org to search by medication name or condition at no cost.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Janssen. Program terms may change — verify current requirements at [https://www.darzalex.com/support](https://www.darzalex.com/support) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Janssen offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Once the JJPAF receives your complete application with all required documents and signatures, a decision is typically made within 2 to 3 business days. Missing documents are the most common cause of delays, so review your application carefully before submitting.
Yes, Medicare patients may still be eligible for the JJPAF program under certain conditions, including being denied coverage for Darzalex or being unable to afford the required cost-share amount. Call (800) 652-6227 to discuss your specific Medicare situation with a program representative.
Yes. The JJPAF requires annual reauthorization to continue receiving Darzalex through the program. It is a good idea to track your approval date and begin the reauthorization process in advance so there is no gap in your medication supply.
You may still be worth applying. The JJPAF notes that higher income thresholds can apply for certain oncology medications or in cases of documented financial hardship. Call (800) 652-6227 to explain your situation before deciding not to apply.
If your application is approved, Darzalex is shipped directly to your prescriber's office, not to your home address. Your healthcare provider's team will notify you when the medication arrives and schedule your treatment from there.
Ready to Apply for Darzalex Assistance?
RX Advantages handles the entire Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month