Dupixent (Asthma) (dupilumab)
Patient Assistance Program Guide — Sanofi Patient Connection
Do You Qualify?
Income
Up to $60,240 for a single person
Insurance
Must be uninsured, underinsured, or have Medicare Part D and be unable to afford the medication.
Residency
U.S. resident with valid address or U.S. Territory resident
Income Limits (400% FPL)
Calculated based on 400% FPL for 2025; some Dupixent-specific programs may have higher thresholds depending on specific plan design but Sanofi Patient Connection baseline is typically 400%.
Based on 2025 HHS Federal Poverty Level guidelines.
# Sanofi Patient Connection: Your Guide to Getting Dupixent (dupilumab) for Asthma at No or Low Cost
Who Qualifies for the Sanofi Patient Connection?
If you have been prescribed Dupixent for asthma and cannot afford it, you may qualify for free or deeply reduced-cost medication through the Sanofi Patient Connection program. To start, if you are a single-person household, your annual income must be at or below $60,240 to meet the baseline income threshold. On the insurance side, you must be either uninsured, underinsured, or enrolled in Medicare Part D and unable to afford your out-of-pocket costs. Patients with full Medicaid coverage are generally not eligible. RX Advantages can help you understand where you stand and walk you through the process of applying.
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About Dupixent (Asthma) (dupilumab)
Dupixent (dupilumab) is a biologic medication that belongs to a drug class called interleukin-4 receptor alpha (IL-4Rα) antagonists. It is FDA-approved to treat moderate-to-severe asthma in certain patients, as well as other conditions including atopic dermatitis, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, and prurigo nodularis. As a biologic, Dupixent is manufactured using complex biological processes, which makes it significantly more expensive than traditional medications. Without insurance or financial assistance, the annual cost can reach tens of thousands of dollars, placing it out of reach for many patients. There are currently no FDA-approved biosimilar versions of dupilumab available.
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Income Eligibility: Full Breakdown
The Sanofi Patient Connection uses income thresholds set at approximately 400% of the Federal Poverty Level (FPL). Here is how that breaks down by household size for 2025:
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $60,240 |
| 2 persons | $81,760 |
| 3 persons | $103,280 |
| 4 persons | $124,800 |
Your household includes everyone living with you who shares finances, such as a spouse or dependents. If your household is larger than four people, the income limit increases with each additional member — contact the program directly to ask about your specific situation.
Income is typically verified using your most recent federal tax return (Form 1040 or W-2), or three months of recent pay stubs if your current income differs from last year. If your income is above these limits, you may not qualify for the free drug program — but you may still be eligible for other savings options, which are covered in the final section of this guide. Do not assume you are ineligible without checking, as Sanofi may consider special circumstances in some cases.
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Insurance Requirements Explained
Understanding your insurance situation is one of the most important steps before applying:
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Step-by-Step: How to Apply
Follow these steps to apply for the Sanofi Patient Connection program for Dupixent:
1. Gather your documents before you start. You will need: a completed application form (patient and prescriber sections), proof of income (IRS Form 1040, W-2, or three months of recent pay stubs), and a valid prescription for Dupixent.
2. Choose your application method. You can apply online, by phone, or by fax:
- Online: Visit www.sanofipatientconnection.com to start your application digitally.
- Phone: Call (888) 847-4877 to speak with a program representative who can guide you through the process.
- Fax: Submit your completed paperwork to (888) 847-1797.
3. Complete the patient section of the application. Fill in your personal, financial, and insurance information accurately and completely.
4. Have your prescriber complete their section. Your doctor or their office staff must fill out the prescriber portion. Many offices are familiar with this process — ask your care team if they can submit their section directly.
5. Submit all documents together. Incomplete applications take longer to process. Double-check that income documentation and the prescription are included.
6. Wait for confirmation. After submission, allow 7 to 10 business days for processing. You will be contacted with a decision.
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What to Expect: Timeline and Delivery
After you submit a complete application, processing typically takes 7 to 10 business days. Sanofi or a program representative will notify you — and usually your prescriber's office — once a decision is made. If approved, your Dupixent will be shipped directly to your home address, so you do not need to pick it up at a pharmacy. Make sure someone is available to receive the shipment, as Dupixent requires specific storage conditions. Approval is not permanent — you will need to reauthorize your enrollment once per year to keep receiving the medication. Watch for renewal notices and prepare updated income documentation ahead of your anniversary date to avoid any gaps in your supply.
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Alternatives If You Don't Qualify
If you do not qualify for the Sanofi Patient Connection, you still have options:
1. Biosimilars: There are currently no FDA-approved biosimilar versions of dupilumab available in the United States, so this is not yet an option for cost savings.
2. Manufacturer savings card (insured patients): If you have commercial insurance, Sanofi offers a Dupixent MyWay Copay Card that may significantly reduce your out-of-pocket costs. You can learn more and enroll at https://www.dupixent.com/asthma/cost-and-savings/copay-card. This card is not available to Medicare or Medicaid patients.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own drug assistance programs, particularly for seniors or people with disabilities. Eligibility and benefits vary by state. Search your state's health department website to find what may be available to you.
4. NeedyMeds.org: This free, independent database at www.needymeds.org lists patient assistance programs, coupons, and other drug cost resources. It is a useful starting point if you are unsure what options exist in your area.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Sanofi / Regeneron. Program terms may change — verify current requirements at [https://www.dupixent.com/support-and-savings/patient-assistance-program](https://www.dupixent.com/support-and-savings/patient-assistance-program) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Sanofi / Regeneron offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Once Sanofi receives your completed application — including all income documents and the prescriber section — processing typically takes 7 to 10 business days. Incomplete applications may take longer, so make sure everything is included before you submit.
If you are approved through the Sanofi Patient Connection, Dupixent is shipped directly to your home. Make sure your address is current on the application and that someone will be available to receive the delivery, since the medication requires proper storage.
Yes, you may still qualify. The Sanofi Patient Connection makes exceptions for Medicare Part D enrollees who cannot afford their out-of-pocket costs. This is different from many other programs that exclude Medicare patients entirely. Contact the program at (888) 847-4877 to discuss your specific situation.
Yes. Approval through the Sanofi Patient Connection is valid for one year. You will need to complete a reauthorization process annually, which typically requires updated income documentation. It is a good idea to start this process a few weeks before your renewal date to avoid any interruption in your medication supply.
It may still be worth contacting the program directly at (888) 847-4877. In some cases, Sanofi may consider your full financial picture, including high medical expenses or other household factors. Even if you do not qualify for the free drug program, you may be eligible for the Dupixent MyWay Copay Card or other assistance options.
Ready to Apply for Dupixent (Asthma) Assistance?
RX Advantages handles the entire Sanofi Patient Connection application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month