Entyvio (vedolizumab)
Patient Assistance Program Guide — Takeda Help at Hand
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Uninsured, underinsured, or patients with government insurance (such as Medicare Part D) who meet financial and medical criteria.
Residency
U.S. resident with a valid address
Income Limits (500% FPL)
Calculations based on 500% of the 2025 Federal Poverty Level, which is the standard threshold for the Takeda Help at Hand patient assistance program for Entyvio.
Based on 2025 HHS Federal Poverty Level guidelines.
# Takeda Help at Hand: A Patient Guide to Getting Entyvio at Low or No Cost
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Who Qualifies for the Takeda Help at Hand?
If you have been prescribed Entyvio (vedolizumab) and are struggling to afford it, you may be able to get it at little or no cost through the Takeda Help at Hand patient assistance program. This program is run directly by Takeda, the company that makes Entyvio. To give you a quick benchmark: if you are a single-person household earning up to $75,300 per year, you may meet the income requirement. On the insurance side, the program is open to patients who are uninsured, underinsured, or covered by a government insurance plan such as Medicare Part D — as long as you also meet the financial and medical criteria. If any of these situations sound like yours, this guide will walk you through exactly how to apply.
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About Entyvio (vedolizumab)
Entyvio is a prescription biologic medication approved by the FDA to treat two chronic inflammatory bowel conditions: ulcerative colitis (UC) and Crohn's disease. It belongs to a drug class called integrin receptor antagonists and is administered by intravenous (IV) infusion. Because Entyvio is a biologic — a complex medication made from living cells — it is significantly more expensive than most traditional drugs. Without insurance or financial assistance, the annual cost can reach tens of thousands of dollars. For patients who depend on it to manage a serious, ongoing condition, that price can make staying on treatment feel impossible. The Takeda Help at Hand program exists specifically to remove that financial barrier.
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Income Eligibility: Full Breakdown
The Takeda Help at Hand program uses 500% of the 2025 Federal Poverty Level (FPL) as its income threshold. The table below shows the maximum annual household income allowed based on household size:
| Household Size | Max Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
If your household has more than four people, the limit continues to increase with each additional member — contact the program directly at (800) 830-7375 to ask about larger household sizes.
Income is typically verified using your most recent federal tax return, a W-2 form, or three months of recent pay stubs. If your income has changed significantly since last year, pay stubs may be the better option to reflect your current situation.
If your income is above the limit for your household size, you may not qualify for free medication through this program. However, you are not necessarily out of options — see the "Alternatives" section below for other programs that may help.
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Insurance Requirements Explained
Your insurance situation affects whether — and how — you qualify. Here is a straightforward breakdown:
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Step-by-Step: How to Apply
1. Gather your documents before you start. You will need: a completed application form (with both your signature and your prescriber's signature), proof of household income (tax return, W-2, or three months of pay stubs), and a valid prescription for Entyvio.
2. Choose how you want to apply. You have multiple options:
- Apply online at https://www.takedahelpathand.com
- Call the program at (800) 830-7375 to apply by phone or request a paper application
- Fax a completed paper application to (866) 246-4441
3. Complete the application with your prescriber. Your doctor or their office staff will need to sign the application. Many practices have experience with this — ask the front desk or a medical assistant for help.
4. Submit all required documents together. Incomplete applications are the most common cause of delays. Double-check that all fields are filled in and all attachments are included before you submit.
5. Wait for a decision. Processing typically takes 7–10 business days after the program receives a complete application.
6. Follow up if needed. If you have not heard back after 10 business days, call (800) 830-7375 to check your application status.
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What to Expect: Timeline and Delivery
Once your application is approved, processing takes approximately 7–10 business days. You or your prescriber's office will receive confirmation of approval. Entyvio can be delivered either to your home or to your prescriber's office or infusion center, depending on how your treatment is set up. Since Entyvio is given by IV infusion, most patients receive it in a clinical setting — your medication may be shipped directly to the infusion site on your behalf. You should not need to pick up or transport the medication yourself.
The program requires annual reauthorization. Before your approval period ends, you will need to reapply and reconfirm that you still meet the eligibility criteria. Mark the date so you are not caught without coverage.
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Alternatives If You Don't Qualify
If you do not qualify for Takeda Help at Hand, here are other avenues to explore:
Biosimilars: As of now, there are no FDA-approved biosimilar versions of Entyvio available in the United States. This may change in the future, so ask your pharmacist or prescriber for updates.
Entyvio Connect Savings Card: If you have commercial (private) insurance, you may be eligible for a savings card through the Entyvio Connect program, which can reduce your out-of-pocket costs. Visit https://www.entyvio.com/entyvioconnect to learn more.
State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own prescription assistance programs, especially for Medicare-eligible residents. Search your state's health department website or ask a benefits counselor.
NeedyMeds.org: This free, nonprofit database lists patient assistance programs, disease-specific funds, and drug discount options. It is a reliable starting point if you are exploring multiple options at once.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Takeda. Program terms may change — verify current requirements at [https://www.entyvio.com/financial-assistance](https://www.entyvio.com/financial-assistance) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Takeda offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Yes. Unlike many patient assistance programs that exclude Medicare Part D beneficiaries, Takeda Help at Hand may accept you if you meet the income and medical criteria. Call (800) 830-7375 to confirm your specific situation before applying.
Once Takeda receives a complete application — including all required signatures and income documentation — a decision is typically made within 7–10 business days. Incomplete applications can delay this timeline.
Yes. The Takeda Help at Hand program requires annual reauthorization. You will need to reconfirm that you still meet the eligibility requirements before your approval period expires to avoid a gap in your medication supply.
If your income is above the program threshold, you may not qualify for Takeda Help at Hand. However, you may be eligible for the Entyvio Connect savings card if you have private insurance, or you can search NeedyMeds.org for other assistance programs that may have different income limits.
Entyvio can be delivered to your home or directly to your prescriber's office or infusion center. Since it is given by IV infusion in a clinical setting, delivery to the infusion site is common. Your approval paperwork will outline the delivery arrangement for your situation.
Ready to Apply for Entyvio Assistance?
RX Advantages handles the entire Takeda Help at Hand application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month