Imfinzi (durvalumab)
Patient Assistance Program Guide — AZ&Me Prescription Savings Program
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Uninsured or Medicare patients who meet specific criteria; commercially insured patients are eligible for the Co-pay Program rather than the free drug program.
Residency
U.S. resident or resident of a U.S. territory with a valid address
Income Limits (500% FPL)
Income threshold for AstraZeneca oncology products is generally set at 500% of the Federal Poverty Level.
Based on 2025 HHS Federal Poverty Level guidelines.
# A Patient Guide to the AZ&Me Prescription Savings Program for Imfinzi (durvalumab)
Prepared by RX Advantages
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Who Qualifies for the AZ&Me Prescription Savings Program?
If you have been prescribed Imfinzi (durvalumab) and are struggling with the cost, the AZ&Me Prescription Savings Program from AstraZeneca may be able to provide it to you at no cost. To qualify for free drug, you generally need to have a household income at or below $75,300 per year for a single-person household — with higher limits for larger families. You also need to meet specific insurance requirements: this free drug program is designed for patients who are uninsured or on Medicare and meet income guidelines. Patients with commercial insurance are typically directed to a separate co-pay assistance program instead. If you are not sure whether you qualify, applying is free and takes only a few steps.
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About Imfinzi (durvalumab)
Imfinzi (durvalumab) is a prescription medicine made by AstraZeneca. It belongs to a class of drugs called PD-L1 blocking antibodies, also known as immune checkpoint inhibitors. Imfinzi has received FDA approval for several serious cancer diagnoses, including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), biliary tract cancer, hepatocellular carcinoma (HCC), and endometrial cancer. It is given as an intravenous (IV) infusion, typically administered in a clinical setting. Without insurance or financial assistance, the cost of Imfinzi can reach tens of thousands of dollars per treatment course, placing it out of reach for many patients. The AZ&Me program exists specifically to help close that gap.
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Income Eligibility: Full Breakdown
AstraZeneca sets income eligibility for Imfinzi at approximately 500% of the Federal Poverty Level. The limits below apply to your total gross household income — meaning everyone living in your home whose income contributes to shared expenses:
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
If your household has more than four people, the limit increases for each additional member. Contact the program directly at (800) 292-6363 for figures beyond four persons.
Income is typically verified using your most recent federal tax return, W-2 forms, or three months of recent pay stubs. If your income has changed significantly since last year — for example, due to job loss or a reduction in hours — you may be able to use current pay stubs to better reflect your situation. If your income is above these thresholds, you may still have options; see the "Alternatives" section below. Program staff can also help you determine whether there is flexibility in how household income is calculated.
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Insurance Requirements Explained
Your insurance status plays a major role in which part of the AZ&Me program applies to you:
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Step-by-Step: How to Apply
Follow these steps to apply for free Imfinzi through the AZ&Me Prescription Savings Program:
1. Gather your documents before you start. You will need: a completed application form (with both your signature and your prescriber's signature), proof of household income (federal tax return, W-2, or three months of recent pay stubs), and a valid prescription for Imfinzi.
2. Choose how you want to apply. You have three options:
- Online: Visit https://www.azandmeapp.com/ to complete and submit your application digitally.
- By phone: Call (800) 292-6363 to speak with a program representative who can walk you through the process.
- By fax: Fax your completed application and supporting documents to (866) 458-0020.
3. Have your prescriber involved. Your doctor or their office staff will need to sign the application. Many offices are familiar with this process and can help coordinate the submission.
4. Submit all documents together. Incomplete applications will cause delays. Make sure your income documents and prescription are included with your application.
5. Wait for a decision. Processing typically takes 2 to 3 business days once a complete application is received.
6. Receive confirmation. You or your prescriber's office will be notified of the approval decision. Keep a copy of your application for your records.
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What to Expect: Timeline and Delivery
Once your application is approved, you can expect a decision within 2 to 3 business days of submitting a complete application. Approved medication is shipped directly to your prescriber's office — not to your home — so your care team can administer it at your scheduled appointment. You do not need to pick up or transport the medication yourself. Your prescriber's office will let you know when the shipment has arrived and schedule your infusion accordingly.
Enrollment in AZ&Me is not permanent. You will need to reapply once per year to continue receiving assistance. Your prescriber's office or RX Advantages can help remind you when renewal is due so there is no gap in your medication supply.
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Alternatives If You Don't Qualify
If you do not qualify for the AZ&Me free drug program, consider these options:
1. Biosimilars: There are currently no FDA-approved biosimilar alternatives to Imfinzi (durvalumab). This may change in the future, so ask your doctor to check for updates.
2. Manufacturer savings card (insured patients): If you have commercial insurance, AstraZeneca offers a co-pay assistance program for Imfinzi. You can learn more and enroll at https://www.myaccess360.com/hcp/imfinzi/patient-support/copay-program.html.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own drug assistance programs, especially for Medicare patients. Your state health department website or your prescriber's office can point you to local resources.
4. NeedyMeds.org: This free, independent database at https://www.needymeds.org lists hundreds of patient assistance programs and discount options by drug name. It is a helpful starting point if other programs have not worked out.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by AstraZeneca. Program terms may change — verify current requirements at [https://www.imfinzi.com/support](https://www.imfinzi.com/support) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
AstraZeneca offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Yes. Unlike many manufacturer assistance programs, AZ&Me is open to qualifying Medicare patients. You will still need to meet the income guidelines — $75,300 per year or less for a single-person household — and complete the standard application. Call (800) 292-6363 if you have questions about how your Medicare coverage affects eligibility.
Processing typically takes 2 to 3 business days after AstraZeneca receives a complete application. Missing documents — such as unsigned forms or incomplete income verification — can delay your approval. Submitting everything together at once is the best way to avoid delays.
Approved Imfinzi is shipped directly to your prescriber's office, not to your home address. Because Imfinzi is given as an IV infusion in a clinical setting, your care team will coordinate the shipment and let you know when your next appointment is scheduled.
Yes. Enrollment in the AZ&Me Prescription Savings Program requires annual reauthorization. You will need to submit an updated application and current income documentation each year to continue receiving assistance. Your prescriber's office or RX Advantages can help you track your renewal date.
If your income is close to but above the published threshold, it is still worth contacting AstraZeneca directly at (800) 292-6363. Program representatives can clarify how household income is calculated and whether any exceptions or flexibility apply to your situation. You may also want to explore the co-pay assistance program if you have commercial insurance.
Ready to Apply for Imfinzi Assistance?
RX Advantages handles the entire AZ&Me Prescription Savings Program application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month