Nplate (romiplostim)
Patient Assistance Program Guide — Amgen Safety Net Foundation
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Must be uninsured, underinsured, or have Medicare Part D and meet specific criteria.
Residency
U.S. resident or resident of U.S. territories with valid address
Income Limits (500% FPL)
Calculated based on 500% FPL; income is based on adjusted gross income (AGI).
Based on 2025 HHS Federal Poverty Level guidelines.
# Getting Nplate (Romiplostim) Through the Amgen Safety Net Foundation: A Patient Guide
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Who Qualifies for the Amgen Safety Net Foundation?
If you need Nplate (romiplostim) and cannot afford it, you may be able to get it at no cost through the Amgen Safety Net Foundation. This program is designed specifically for patients who face financial barriers to accessing Amgen medications, including Nplate. If you are a single-person household, your annual income must be at or below $75,300 to qualify. To be eligible, you must be uninsured, underinsured, or enrolled in Medicare Part D and meet specific additional criteria set by the program. If you meet these requirements, the Amgen Safety Net Foundation may provide Nplate to you free of charge. RX Advantages can help you understand whether you may qualify and walk you through the application process.
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About Nplate (Romiplostim)
Nplate (romiplostim) is a prescription medication made by Amgen. It is FDA-approved to treat immune thrombocytopenia (ITP) in adults and children, a condition where the immune system attacks platelets, leading to low platelet counts and increased bleeding risk. Nplate is also approved for use in Hematopoietic Syndrome of Acute Radiation Syndrome. It belongs to a class of drugs called thrombopoietin (TPO) receptor agonists, which work by stimulating the body to produce more platelets. Because Nplate is a specialty biologic medication administered by a healthcare provider, its list price is very high — often placing it out of reach for patients without comprehensive insurance coverage.
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Income Eligibility: Full Breakdown
The Amgen Safety Net Foundation uses 500% of the Federal Poverty Level (FPL) to determine income eligibility. Your income is based on your adjusted gross income (AGI), which is the figure found on your federal tax return. The income limits by household size are as follows:
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
If your household has more than four people, the income limit increases with each additional member, following the same FPL-based formula.
To verify your income, you will typically need to provide your most recent federal tax return or three consecutive months of recent pay stubs. If your income has changed significantly since last year — for example, due to job loss — pay stubs may better reflect your current situation and may be more helpful than a prior-year tax return.
If your income is above these limits, you may not qualify for this program. However, there are other options available, which are covered in the "Alternatives" section below.
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Insurance Requirements Explained
Your insurance status plays an important role in determining whether you qualify. Here is how the program handles different situations:
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Step-by-Step: How to Apply
Follow these steps to apply for Nplate through the Amgen Safety Net Foundation:
1. Gather your documents. You will need: proof of income (prior-year federal tax return, W-2, or three months of recent pay stubs), a copy of your insurance card if you have insurance, and a completed application form with your prescribing physician's signature.
2. Choose your application method. You can apply in one of three ways:
- Online: Visit https://www.amgensafetynetfoundation.com to complete and submit your application electronically.
- By phone: Call (888) 762-6436 to speak with a program representative who can guide you through the process.
- By fax: Fax your completed application and supporting documents to (866) 549-7239.
3. Have your doctor involved. Your prescribing physician must sign the application. Many practices handle this routinely — ask your doctor's office if they are familiar with the Amgen Safety Net Foundation.
4. Submit all required documents at the same time. Incomplete applications can cause delays. Double-check that your income documentation, application form, and insurance card copy (if applicable) are all included.
5. Wait for confirmation. After submission, the program typically processes applications within 1–2 business days. You or your doctor's office will receive confirmation of approval or a request for additional information.
6. Follow up if needed. If you have not heard back within three business days, call (888) 762-6436 to check on your application status.
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What to Expect: Timeline and Delivery
Once your application is approved — typically within 1–2 business days — Amgen will notify your prescriber. Nplate is shipped directly to your prescribing physician's office, not to your home. This is because Nplate is administered by a healthcare provider. You do not need to arrange a pickup separately; your doctor's office will contact you to schedule your appointment once the medication arrives. The Amgen Safety Net Foundation requires annual reauthorization, meaning you will need to reapply and reconfirm your eligibility each year to continue receiving the medication at no cost.
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Alternatives If You Don't Qualify
If you do not meet the requirements for the Amgen Safety Net Foundation, here are other options to explore:
1. Biosimilars: There are currently no FDA-approved biosimilars for Nplate (romiplostim). This means a lower-cost biosimilar version is not yet available as an alternative.
2. Manufacturer savings card (for insured patients): If you have commercial insurance and need help with your copay, Amgen offers the Amgen SupportPlus Co-Pay Program. You can learn more and enroll at https://www.nplate.com/financial-support/amgen-supportplus-co-pay-program. Note that this program is not available to Medicare or Medicaid patients.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer programs that help residents pay for prescription medications. Eligibility and benefits vary by state. Contact your state's department of health or aging to find out what programs may be available to you.
4. NeedyMeds.org: This free, independent website maintains a searchable database of patient assistance programs, copay assistance, and other drug cost resources. Visit https://www.needymeds.org to search by drug name or condition.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Amgen. Program terms may change — verify current requirements at [https://www.nplate.com/patient-caregiver/support](https://www.nplate.com/patient-caregiver/support) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Amgen offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Most applications are processed within 1 to 2 business days after all required documents are received. Make sure your application is complete — including your income documentation and your doctor's signature — to avoid delays.
No. Because Nplate is administered by a healthcare provider, it is shipped directly to your prescribing physician's office. Your doctor's office will contact you to schedule an appointment once the medication arrives.
Yes. The Amgen Safety Net Foundation requires annual reauthorization. Before your approval period ends, you will need to resubmit income documentation and a new completed application to continue receiving Nplate at no cost.
You may be eligible. Unlike many manufacturer programs that exclude Medicare patients entirely, the Amgen Safety Net Foundation has specific provisions for patients with Medicare Part D who meet the income and other criteria. Call (888) 762-6436 to discuss your specific situation with a program representative.
If your adjusted gross income is above the threshold for your household size, you may not qualify for the Amgen Safety Net Foundation. However, you may still be able to get help through the Amgen SupportPlus Co-Pay Program if you have commercial insurance, your state's pharmaceutical assistance program, or resources listed at NeedyMeds.org.
Ready to Apply for Nplate Assistance?
RX Advantages handles the entire Amgen Safety Net Foundation application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month