Praluent (alirocumab)
Patient Assistance Program Guide — Sanofi Patient Connection
Do You Qualify?
Income
Up to $60,240 for a single person
Insurance
Must be uninsured, underinsured, or have a Medicare Part D plan with a coverage gap or financial hardship.
Residency
U.S. resident with valid address
Income Limits (400% FPL)
Calculated based on 400% of the 2025 Federal Poverty Level (FPL) as is standard for Sanofi specialty medications like Praluent.
Based on 2025 HHS Federal Poverty Level guidelines.
# Getting Praluent (Alirocumab) at No Cost Through Sanofi Patient Connection
Who Qualifies for the Sanofi Patient Connection?
If you need Praluent (alirocumab) but cannot afford it, you may be able to get it for free through the Sanofi Patient Connection patient assistance program. This program is designed specifically for patients who are uninsured, underinsured, or struggling to cover costs even with insurance. For a single-person household, the maximum annual income allowed is $60,240. To qualify, you must either have no insurance coverage, have insurance that does not adequately cover Praluent, or have a Medicare Part D plan where cost-sharing creates a financial hardship. If you meet the income and insurance criteria, Sanofi may provide Praluent at no charge, shipped directly to your home.
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About Praluent (Alirocumab)
Praluent (alirocumab) is a prescription injectable medication manufactured by Sanofi and Regeneron. It belongs to a class of drugs called PCSK9 inhibitors and is FDA-approved to treat adults with primary hypercholesterolemia, certain forms of hyperlipidemia, and atherosclerotic cardiovascular disease (ASCVD). Praluent is administered by injection under the skin, typically every two to four weeks. Without insurance or financial assistance, the list price for Praluent can exceed $6,000 per year, placing it out of reach for many patients. Because of this high cost, Sanofi created the Sanofi Patient Connection program to help eligible patients access the medication at little or no cost.
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Income Eligibility: Full Breakdown
Sanofi Patient Connection uses 400% of the Federal Poverty Level (FPL) as its income threshold — a standard used across many of Sanofi's specialty medication assistance programs. The income limits for 2025 are:
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $60,240 |
| 2 persons | $81,760 |
| 3 persons | $103,280 |
| 4 persons | $124,800 |
Your income is typically verified using your most recent federal tax return (Form 1040 or W-2) or three consecutive recent pay stubs. Sanofi looks at your household income, meaning the combined income of everyone living in your home who files taxes together. If your household has more than four people, the income limit increases — contact Sanofi directly to ask about the threshold for your household size.
If your income is above these limits, you may not qualify for free medication through this program. However, you are not without options — see the "Alternatives If You Don't Qualify" section below for other resources that may still help reduce your costs.
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Insurance Requirements Explained
Your insurance status plays a major role in determining eligibility. Here is how different situations are handled:
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Step-by-Step: How to Apply
1. Check your eligibility first. Review the income table and insurance criteria above. If you are unsure, call Sanofi Patient Connection at (888) 847-4877 to speak with a representative before gathering documents.
2. Gather your required documents. You will need:
- Proof of income: your most recent Form 1040 tax return, W-2, or three consecutive recent pay stubs
- A valid prescription for Praluent from your healthcare provider
- Completed patient section of the application
- Completed healthcare provider section (your doctor must sign this portion)
3. Choose how to apply. You have multiple options:
- Online: Visit https://www.sanofipatientconnection.com/ to start an application digitally. This is often the fastest method.
- By fax: Fax completed forms and documents to (888) 847-1797.
- By phone: Call (888) 847-4877 to apply with assistance from a program representative.
4. Submit your healthcare provider's section. Your doctor must complete and sign their portion of the application. Many offices are familiar with this process, but you may need to remind them to submit their section promptly.
5. Wait for confirmation. After your application is submitted with all required documents, processing typically takes 2 to 5 business days.
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What to Expect: Timeline and Delivery
Once your application is approved, Sanofi will notify you — and often your prescriber's office — of your enrollment status. Praluent is shipped directly to your home address, so you do not need to visit a pharmacy for pickup. Make sure your address on the application is current and that someone will be available to receive a temperature-sensitive package if required. Your approval is valid for one year, after which you must reauthorize. Sanofi typically sends a reminder when renewal is approaching, but it is a good idea to mark your calendar and start the renewal process a few weeks before your approval expires to avoid any gap in medication.
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Alternatives If You Don't Qualify
If you do not meet the eligibility requirements for Sanofi Patient Connection, consider these options:
1. Biosimilars: As of the publication of this guide, there are no FDA-approved biosimilar alternatives to Praluent currently available in the United States. This may change in the future, so ask your pharmacist or doctor about updates.
2. Praluent myWay Savings Card (for insured patients): If you have commercial insurance, Sanofi offers a savings card program called Praluent myWay that may significantly reduce your out-of-pocket costs. Learn more and enroll at https://www.praluent.com/praluent-myway. Note that this card is generally not available to Medicare or Medicaid patients.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own prescription assistance programs for residents who do not qualify for federal programs. Search for your state's SPAP through your state health department website or ask your doctor's office for a referral.
4. NeedyMeds.org: This free, independent database at https://www.needymeds.org lists hundreds of assistance programs by drug name, condition, and state. It is a helpful starting point if other options fall short.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Sanofi / Regeneron. Program terms may change — verify current requirements at [https://www.praluent.com/patient-assistance-program](https://www.praluent.com/patient-assistance-program) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Sanofi / Regeneron offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Once Sanofi Patient Connection receives your completed application — including the patient section, healthcare provider section, proof of income, and a valid prescription — processing typically takes 2 to 5 business days. After approval, the medication is shipped directly to your home. Allow additional time for shipping when planning ahead.
Yes. Your enrollment in Sanofi Patient Connection is approved for one year at a time. You will need to reauthorize annually by submitting updated income documentation and a renewed prescription. Sanofi typically sends a reminder before your approval expires, but it is a good idea to begin the renewal process a few weeks early to avoid any interruption in your medication supply.
Possibly. Sanofi Patient Connection does accept some patients with Medicare Part D coverage, particularly those who are in a coverage gap or who can demonstrate financial hardship related to their drug costs. Not all Medicare enrollees will qualify, so contact the program at (888) 847-4877 to discuss your specific situation before applying.
If your income exceeds the threshold for your household size, you may not qualify for free medication through this program. However, if you have commercial insurance, you may still be eligible for the Praluent myWay savings card at https://www.praluent.com/praluent-myway. You can also explore state pharmaceutical assistance programs or search NeedyMeds.org for other options that may fit your situation.
Yes. RX Advantages is a prescription assistance service that can help guide you through the application process for programs like Sanofi Patient Connection. We can help you understand the requirements, gather your documents, and navigate the steps — though eligibility decisions are made solely by Sanofi, not by RX Advantages.
Ready to Apply for Praluent Assistance?
RX Advantages handles the entire Sanofi Patient Connection application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
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