Sarclisa (isatuximab)
Patient Assistance Program Guide — Sanofi CareASSIST Patient Support
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Uninsured, underinsured, or Medicare patients with inadequate coverage; commercially insured patients are typically directed to the copay program first.
Residency
U.S. resident or resident of U.S. territories with a valid address
Income Limits (500% FPL)
Income threshold calculated at 500% FPL based on standard Sanofi Oncology assistance criteria.
Based on 2025 HHS Federal Poverty Level guidelines.
# A Patient Guide to Sanofi CareASSIST for Sarclisa (Isatuximab)
Prepared by RX Advantages
---
Who Qualifies for the Sanofi CareASSIST Patient Support?
If you have been prescribed Sarclisa (isatuximab) for multiple myeloma and cannot afford your medication, you may be able to receive it at no cost through the Sanofi CareASSIST Patient Support program. This program is designed to help patients who are uninsured, underinsured, or covered by Medicare with gaps in coverage. For a single-person household, the maximum annual income allowed is $75,300. Patients with commercial (private) insurance are typically directed to a separate copay assistance program rather than the free drug program. If you meet the income and insurance criteria, Sanofi CareASSIST may be able to provide Sarclisa at no charge to you.
---
About Sarclisa (Isatuximab)
Sarclisa (isatuximab) is a prescription medication made by Sanofi. It belongs to a drug class called CD38-directed cytolytic antibodies and is approved by the FDA to treat adults with multiple myeloma, a type of blood cancer. Sarclisa is given by intravenous (IV) infusion, typically in combination with other cancer medications. As a specialty biologic drug, Sarclisa carries a very high list price that can reach tens of thousands of dollars per treatment cycle. Without insurance coverage or financial assistance, most patients would be unable to afford this therapy. Patient assistance programs like Sanofi CareASSIST exist specifically to help close this gap.
---
Income Eligibility: Full Breakdown
The Sanofi CareASSIST program uses household size and annual income to determine eligibility. The income limits below are based on approximately 500% of the Federal Poverty Level (FPL):
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
If your household size is larger than four people, there may be additional flexibility in the income threshold — ask the program coordinator when you call.
Your income is typically verified using your most recent federal tax return, your most recent W-2, or three months of recent pay stubs. If your income has changed significantly since last year — for example, due to job loss or retirement — you may be able to use current pay stubs instead of a prior-year tax return to reflect your actual financial situation.
If your income is above the listed limits, you may not qualify for free medication through this program. However, you should still explore the copay savings card (for insured patients) or other alternatives described at the end of this guide. Program income thresholds can also change, so it is worth checking directly with Sanofi CareASSIST even if you are unsure whether you qualify.
---
Insurance Requirements Explained
Your insurance status plays an important role in how Sanofi CareASSIST can help you. Here is how each situation is typically handled:
---
Step-by-Step: How to Apply
Follow these steps to apply for Sanofi CareASSIST for Sarclisa:
1. Gather your documents before you start. You will need: a completed and signed Patient Authorization Form, proof of household income (most recent tax return, W-2, or three months of pay stubs), any insurance cards you have, and a completed medical section and valid prescription filled out by your prescribing doctor.
2. Choose your application method. You can apply in three ways:
- Online: Visit https://www.sanoficareassist.com/sarclisa to start an online application.
- By phone: Call (833) 722-7747 to speak with a program representative who can guide you through the process.
- By fax: Fax your completed application and supporting documents to (855) 411-9689.
3. Involve your prescriber early. Your doctor or their office staff will need to complete and sign portions of the application, including the medical section and the prescription. Many prescriber offices are familiar with this process — ask your care team for help.
4. Submit all documents together. Incomplete applications can slow down processing. Make sure every required form is signed and every income document is included before submitting.
5. Wait for a determination. Processing typically takes 1 to 2 business days after a complete application is received.
6. Confirm approval with your prescriber's office. Once approved, your care team will be notified and can coordinate next steps for your treatment.
---
What to Expect: Timeline and Delivery
Once your completed application is submitted, a decision is typically made within 1 to 2 business days. You will not need to pick up Sarclisa at a pharmacy. If approved, the medication is shipped directly to your prescriber's office or infusion center — not to your home. Your care team will contact you to schedule your infusion appointment. You do not need to do anything special at the time of your infusion related to the assistance program.
Approval through Sanofi CareASSIST is not permanent. You will need to reapply once per year to continue receiving assistance. Your prescriber's office may help coordinate this renewal, but it is a good idea to track your approval date and plan ahead.
---
Alternatives If You Don't Qualify
If you do not qualify for the Sanofi CareASSIST free drug program, consider these options:
1. Biosimilar alternatives: There are currently no FDA-approved biosimilars for Sarclisa (isatuximab). This option is not available at this time.
2. Sanofi CareASSIST Copay Savings Card: If you have commercial (private) insurance, you may qualify for the Sarclisa copay program, which can reduce your out-of-pocket costs significantly. Visit https://www.sanoficareassist.com/sarclisa/copay-program for details.
3. State Pharmaceutical Assistance Programs (SPAP): Many states offer their own prescription assistance programs, particularly for seniors or people with disabilities. Your State Health Insurance Assistance Program (SHIP) counselor can help you find local options.
4. NeedyMeds.org: This free, nonprofit database at www.needymeds.org lists hundreds of patient assistance programs, disease-specific funds, and other resources that may apply to your situation. It costs nothing to search.
---
*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Sanofi. Program terms may change — verify current requirements at [https://www.sarclisa.com/support](https://www.sarclisa.com/support) before applying.*
---
Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Sanofi offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Once Sanofi receives a complete application with all required documents, a decision is typically made within 1 to 2 business days. Missing documents are the most common cause of delays, so make sure your income proof, signed patient authorization, and your doctor's completed medical section are all included before submitting.
No. If your application is approved, Sarclisa is shipped directly to your prescriber's office or infusion center, not to your home. Your care team will notify you when the medication is ready and schedule your infusion appointment.
Yes, you can still apply if you have Medicare. Unlike some manufacturer programs, Sanofi CareASSIST has provisions for Medicare patients who have inadequate coverage or face costs they cannot afford. Submit an application and let the program review your specific situation.
Yes. Sanofi CareASSIST approval lasts for one year. You will need to reauthorize your enrollment annually to continue receiving Sarclisa through the program. It is a good idea to note your approval date and begin the renewal process before it expires so there is no gap in your treatment.
You should still contact Sanofi CareASSIST directly by calling (833) 722-7747. Income thresholds can sometimes be reviewed on a case-by-case basis, and program terms may be updated. Even if you do not qualify for the free drug program, you may be eligible for the copay savings card or other forms of financial support.
Ready to Apply for Sarclisa Assistance?
RX Advantages handles the entire Sanofi CareASSIST Patient Support application on your behalf — paperwork, physician coordination, and refill tracking. It takes about 15 minutes to get started.
No SSN required on the web form · From $49.95/month