Spravato (esketamine)

Do You Qualify?

Income Limits (300% FPL)

Calculated based on 300% of 2025 FPL; patient must have no other insurance coverage or meet specific criteria for Medicare Part D.

Based on 2025 HHS Federal Poverty Level guidelines.

# Getting Spravato (Esketamine) for Free or Reduced Cost Through the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)

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Who Qualifies for the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)?

If you need Spravato (esketamine) but cannot afford it, the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF) may be able to provide it at no cost to you. This program is designed for patients who meet specific income and insurance requirements. For a single-person household, your annual income must be at or below $45,180 to qualify. On the insurance side, you must be uninsured, underinsured, or have Medicare Part D coverage with no other outpatient prescription drug assistance available to you. If you meet these basic criteria, this program may cover the full cost of your Spravato treatment — with no purchase price charged to you directly.

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About Spravato (Esketamine)

Spravato (esketamine) is a prescription nasal spray made by Janssen, a Johnson & Johnson company. It is FDA-approved to treat two specific conditions in adults: treatment-resistant depression (TRD), meaning depression that has not responded adequately to other antidepressants, and depressive symptoms in adults with major depressive disorder (MDD) who have acute suicidal ideation or behavior. Spravato belongs to a drug class called NMDA receptor antagonists. Because it must be administered in a certified healthcare setting under medical supervision, its costs — including the medication itself and the clinical visits — can be significant. Without insurance or assistance, many patients find it financially out of reach.

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Income Eligibility: Full Breakdown

The JJPAF uses income thresholds set at 300% of the 2025 Federal Poverty Level (FPL). The limits by household size are:

| Household Size | Maximum Annual Income |

|---|---|

| 1 person | $45,180 |

| 2 persons | $61,320 |

| 3 persons | $77,460 |

| 4 persons | $93,600 |

Your household size includes everyone who lives with you and shares finances, such as a spouse, partner, or dependents. If your household is larger than four people, income limits increase incrementally — contact the program directly at (800) 652-6227 to ask about your specific situation.

To verify your income, you will typically need to submit your most recent U.S. Income Tax Return (Form 1040). If your tax return is unavailable — for example, if you did not file or recently had a major income change — you may instead provide proof of income such as three months of recent pay stubs, a Social Security award letter, or similar documentation.

If your income is above the listed thresholds, you may not qualify for JJPAF. However, you are not necessarily without options. Scroll to the "Alternatives" section below for other programs that may still be able to help you.

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Insurance Requirements Explained

Your insurance status plays a major role in determining whether you qualify. Here is how each situation is handled:

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Step-by-Step: How to Apply

Follow these steps to apply for Spravato through the JJPAF:

1. Gather your documents before you start. You will need your most recent U.S. Income Tax Return (Form 1040). If that is not available, collect proof of income such as three months of pay stubs. You will also need a completed and signed prescriber section of the application — your doctor must sign off.

2. Choose your application method. You can apply online at https://www.jjpaf.org/, which is the fastest option. Alternatively, you can call (800) 652-6227 to request a paper application or get help by phone. If your provider prefers to submit on your behalf, paper applications can be faxed to (888) 526-5168.

3. Complete the application fully. Incomplete applications are a common cause of delays. Make sure all fields are filled in and that your prescriber has signed their section before submission.

4. Submit your supporting documents. Attach your income documentation when submitting online or by fax. Keep a copy of everything you send.

5. Follow up if needed. If you have not heard back within 10 business days, call (800) 652-6227 to check your application status.

6. Notify your prescriber. Once approved, your doctor's office will be notified and will coordinate receiving the medication on your behalf.

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What to Expect: Timeline and Delivery

After submitting a complete application, processing typically takes 7 to 10 business days. Once approved, the JJPAF will notify your prescriber's office directly. Spravato is shipped to your prescriber — not to your home — which is consistent with how the medication is administered (always in a certified clinical setting under supervision). You do not need to pick up or handle the shipment yourself. Your prescriber's office will schedule your treatment sessions as the medication becomes available. Approval through this program is not permanent — you will need to reapply for reauthorization once per year to continue receiving benefits. Your prescriber's office may assist with this renewal.

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Alternatives If You Don't Qualify

If you do not meet the JJPAF income or insurance requirements, consider these options:

1. Biosimilars: There are currently no FDA-approved biosimilar or generic alternatives to Spravato (esketamine). This may change in the future, but for now, Spravato is only available as a brand-name product.

2. Manufacturer savings card: If you have private insurance that covers Spravato, Janssen CarePath offers a cost-support savings card that may reduce your out-of-pocket costs. You can learn more and enroll at https://www.janssencarepath.com/patient/spravato/cost-support.

3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own drug assistance programs, especially for residents who are seniors or have disabilities. Search your state's health department website to find programs in your area.

4. NeedyMeds.org: This free, independent database lists hundreds of patient assistance programs, disease-based funds, and other cost-reduction resources. Visit https://www.needymeds.org to search by drug name or diagnosis at no charge.

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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Janssen. Program terms may change — verify current requirements at [https://www.spravatohcp.com/support](https://www.spravatohcp.com/support) before applying.*

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