Takhzyro (lanadelumab)
Patient Assistance Program Guide — Takeda Help at Hand
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Must be uninsured, underinsured, or have commercial insurance that does not cover the medication. Patients with government insurance are generally ineligible for co-pay cards but may qualify for PAP based on clinical and financial need.
Residency
U.S. resident or U.S. territory resident
Income Limits (500% FPL)
Calculated based on 500% FPL for rare disease medications under Takeda Help at Hand program.
Based on 2025 HHS Federal Poverty Level guidelines.
# Takeda Help at Hand: Your Guide to Getting Takhzyro at Low or No Cost
Who Qualifies for the Takeda Help at Hand?
If you have been prescribed Takhzyro (lanadelumab) and are struggling with the cost, you may be able to get it free or at a reduced cost through the Takeda Help at Hand patient assistance program. This program is designed specifically for patients who need financial support to access Takhzyro. For a single-person household, your annual income must be at or below $75,300 to qualify. In terms of insurance, you must be uninsured, underinsured, or have commercial insurance that does not adequately cover this medication. If you have government-funded insurance such as Medicare or Medicaid, different rules apply, which are explained in detail below.
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About Takhzyro (lanadelumab)
Takhzyro is a prescription injectable medication made by Takeda. It is FDA-approved for the prevention of hereditary angioedema (HAE) attacks in adults and pediatric patients 12 years and older who have HAE Type I or Type II. Takhzyro belongs to a class of drugs called plasma kallikrein inhibitors and works as a monoclonal antibody. Without insurance or financial assistance, the list price of Takhzyro can reach tens of thousands of dollars per month, placing it out of reach for many patients. The Takeda Help at Hand program exists to help bridge that gap for eligible individuals.
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Income Eligibility: Full Breakdown
Takeda Help at Hand uses income thresholds based on approximately 500% of the Federal Poverty Level, which is a standard used for rare disease medications. The income limits by household size are as follows:
| Household Size | Max Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
Your income is typically verified using your most recent federal tax return (Form 1040 or W-2) or three months of recent pay stubs. If your household size is larger than four people, contact Takeda Help at Hand directly to ask about your specific situation, as the program may have flexibility beyond the published table.
If your income is above these limits, you may not qualify for free medication through the patient assistance program. However, you may still be eligible for the Takhzyro co-pay savings card if you have commercial insurance. Other options are outlined in the "Alternatives" section below. Do not assume you are ineligible without speaking with a program representative — income from certain sources may be calculated differently, and it is always worth asking.
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Insurance Requirements Explained
Your insurance situation plays a major role in how Takeda Help at Hand can help you:
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Step-by-Step: How to Apply
Follow these steps to apply for Takeda Help at Hand:
1. Gather your documents. You will need a completed application form with your physician's signature, proof of household income (such as your most recent Form 1040, W-2, or three months of pay stubs), and a valid prescription for Takhzyro.
2. Choose your application method. You can apply online, by phone, or by fax.
- Online: Visit https://www.takedahelpathand.com/ to complete and submit your application digitally.
- By phone: Call (800) 830-9361 to speak with a program representative who can walk you through the process.
- By fax: Send your completed application and supporting documents to (866) 825-3321.
3. Have your doctor complete their portion. The application requires a physician signature, so make sure your prescribing doctor is aware and prepared to sign.
4. Submit all required documents together. Incomplete applications can delay processing, so confirm everything is included before submitting.
5. Wait for a decision. Processing typically takes 2 to 4 business days after your complete application is received.
6. Confirm approval and arrange delivery. Once approved, you will be notified and your medication will be arranged for shipment directly to your home.
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What to Expect: Timeline and Delivery
After you submit a complete application, expect a decision within 2 to 4 business days. You will typically be notified of approval by phone or mail. If approved, Takhzyro is shipped directly to your home — you do not need to pick it up at a pharmacy or your doctor's office. You should not need to take any additional steps at delivery beyond receiving the package.
Because Takhzyro is an injectable medication, make sure you have spoken with your doctor or nurse about proper storage and administration before your first shipment arrives.
Your enrollment in the program must be renewed annually. You will need to resubmit income documentation and an updated application each year to continue receiving assistance. Plan ahead so there is no gap in your medication supply.
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Alternatives If You Don't Qualify
If you do not qualify for the Takeda Help at Hand patient assistance program, you still have options:
1. Biosimilars: There are currently no FDA-approved biosimilar alternatives to Takhzyro. This option is not available at this time.
2. Manufacturer co-pay savings card: If you have commercial insurance, you may be eligible for the Takhzyro co-pay program, which can reduce your out-of-pocket costs. Learn more at https://www.takhzyro.com/patient-support/copay-program.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer programs that help residents pay for high-cost medications. Eligibility and benefits vary by state. Contact your state's department of health or aging to ask what may be available to you.
4. NeedyMeds.org: This free, independent database lists hundreds of patient assistance programs and drug discount options. Visit https://www.needymeds.org to search by medication name and explore additional resources that may help cover your costs.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Takeda. Program terms may change — verify current requirements at [https://www.takhzyro.com/patient-support](https://www.takhzyro.com/patient-support) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Takeda offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Once Takeda receives your complete application — including your physician signature, income documents, and prescription — processing typically takes 2 to 4 business days. Incomplete applications may take longer, so make sure all required documents are included before you submit.
Patients with Medicare are generally not eligible for the Takhzyro co-pay savings card. However, you may still be reviewed for the patient assistance program based on your financial and clinical situation. Call (800) 830-9361 to speak with a representative about your specific circumstances.
You must reapply for the Takeda Help at Hand program every year. This means submitting an updated application form with a physician signature, current income documentation, and a new prescription if needed. Plan to start the renewal process a few weeks before your current enrollment expires to avoid any gap in coverage.
No. As of now, there are no FDA-approved biosimilar alternatives to Takhzyro (lanadelumab). If you are looking for lower-cost options, the manufacturer co-pay card or state pharmaceutical assistance programs may be worth exploring depending on your insurance situation.
It is still worth applying or calling the program at (800) 830-9361. In some cases, program representatives can review exceptions or help you understand if any income sources are calculated differently. You may also qualify for the co-pay savings card if you have commercial insurance, regardless of income.
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