Oncology

Talzenna (talazoparib)

Patient Assistance Program Guide — Pfizer Oncology Together

Verified: February 27, 2026
Pfizer Oncology Together
Program name
2-3 business days
Processing time
shipped to patient
Medication delivery
$75,300
1-person income limit

Do You Qualify?

Income

Up to $75,300 for a single person

Insurance

Uninsured, underinsured, or Medicare patients who meet financial criteria

Residency

U.S. resident with valid address

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Income Limits (500% FPL)

Household SizeMax Annual Income
1 person$75,300
2 persons$102,200
3 persons$129,100
4 persons$156,000

Income limits calculated at 500% of the 2025 FPL, which is standard for Pfizer's Oncology Patient Assistance Foundation.

Based on 2025 HHS Federal Poverty Level guidelines.

# Pfizer Oncology Together: A Patient Guide to Free or Reduced-Cost Talzenna (Talazoparib)

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Who Qualifies for Pfizer Oncology Together?

If you have been prescribed Talzenna (talazoparib) and are struggling to afford it, you may qualify to receive it at no cost through Pfizer Oncology Together, Pfizer's patient assistance program. For a single-person household, your annual income must be at or below $75,300 to meet the financial criteria. If you have no insurance, have Medicare, or have private insurance that does not fully cover Talzenna, you may still be eligible. Medicaid patients are generally not eligible for this program. Approval is based on both your income and your insurance status, but the program is designed to help patients across a range of financial situations get the medication their doctor has prescribed.

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About Talzenna (Talazoparib)

Talzenna (talazoparib) is an oral prescription medication manufactured by Pfizer. It belongs to a class of drugs called PARP inhibitors, which work by interfering with a cancer cell's ability to repair its DNA. Talzenna is FDA-approved for adults with BRCA-mutated, HER2-negative locally advanced or metastatic breast cancer, as well as for metastatic castration-resistant prostate cancer (mCRPC). Without insurance or financial assistance, the monthly cost of Talzenna can reach several thousand dollars, placing it out of reach for many patients. Because no FDA-approved biosimilar or generic version currently exists, the brand-name medication is the only option available, making patient assistance programs especially important for those who cannot afford the list price.

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Income Eligibility: Full Breakdown

Pfizer Oncology Together uses income thresholds set at 500% of the 2025 Federal Poverty Level (FPL). The table below shows the maximum annual income allowed for each household size:

| Household Size | Maximum Annual Income |

|---|---|

| 1 person | $75,300 |

| 2 persons | $102,200 |

| 3 persons | $129,100 |

| 4 persons | $156,000 |

Your household income is typically verified using your most recent federal tax return, a W-2 form, or three consecutive months of pay stubs. If your income situation has changed recently — such as a job loss or reduction in hours — pay stubs may better reflect your current circumstances than last year's tax return.

If your income is above these limits, you will likely not qualify for free medication through this program. However, you are not without options. Pfizer may have other resources available, and insured patients who exceed the income threshold may be eligible for the Talzenna savings card program instead. See the "Alternatives" section below for more details. Household size matters: a family of four with the same income as a single person may still qualify, so make sure you report your full household accurately on the application.

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Insurance Requirements Explained

Your insurance status plays a direct role in whether you qualify. Here is how different situations are handled:

If you are uninsured: You may qualify for free Talzenna directly through Pfizer Oncology Together, provided you also meet the income requirements.
If you have Medicare Part D: You may still be eligible. Unlike some manufacturer assistance programs, Pfizer Oncology Together does accept Medicare patients who meet the financial criteria. Medicare patients are not automatically excluded.
If you have private insurance that covers Talzenna only partially or not at all: You may qualify as "underinsured." If your out-of-pocket costs remain unaffordable after insurance, the program may be able to help cover what your plan does not.
If you have Medicaid: Patients with Medicaid are generally not eligible for this program. Federal rules typically prevent manufacturer assistance programs from coordinating with Medicaid coverage. You may want to explore state pharmaceutical assistance programs (SPAPs) instead.

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Step-by-Step: How to Apply

Follow these steps to apply for Talzenna at no cost through Pfizer Oncology Together:

1. Gather your documents. You will need proof of income (your most recent federal tax return, W-2, or three months of recent pay stubs), your prescription information for Talzenna, and a completed Patient and Prescriber Enrollment Form.

2. Download or request the enrollment form. Visit the program website at https://www.pfizeroncologytogether.com to access the enrollment form. Your doctor's office may also have copies on hand.

3. Have your prescriber complete their section. Your doctor or their office staff must fill out the prescriber portion of the enrollment form. Many oncology offices handle this routinely — ask your care team for help if needed.

4. Choose your submission method. You can apply in one of three ways:

- Online: Submit your application at https://www.pfizeroncologytogether.com

- Phone: Call (877) 744-5675 to apply with a program representative

- Fax: Fax your completed form and documents to (877) 733-7604

5. Confirm receipt. After submitting, follow up to confirm your application was received, especially if faxing.

6. Wait for a decision. Processing typically takes 2 to 3 business days after all required documents are received.

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What to Expect: Timeline and Delivery

Once your application is approved, Pfizer Oncology Together will notify you and your prescriber of the decision. Most applications are processed within 2 to 3 business days, as long as all required documents have been submitted. If something is missing, a program representative may contact you or your doctor's office to request additional information.

Approved medication is shipped directly to your home, so you do not need to pick it up at a pharmacy. You do not need to take any action at the time of delivery beyond being available to receive the package. Your enrollment must be renewed annually — you will need to reapply and resubmit updated income documentation each year to continue receiving benefits.

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Alternatives If You Don't Qualify

If you do not meet the eligibility requirements for Pfizer Oncology Together, consider these options:

1. Biosimilars or generics: There are currently no FDA-approved biosimilars or generic versions of Talzenna available. This means lower-cost substitutes are not yet an option.

2. Pfizer savings card for insured patients: If you have commercial insurance and do not qualify for the free medication program, Pfizer offers a separate savings card that may reduce your out-of-pocket costs. Learn more at https://www.talzenna.com/savings-and-support.

3. State Pharmaceutical Assistance Programs (SPAPs): Many states offer their own drug assistance programs for residents who do not qualify for manufacturer programs. Eligibility and benefits vary by state. Contact your state's department of health or aging to ask about available programs.

4. NeedyMeds.org: This free, nonprofit database at www.needymeds.org lists hundreds of patient assistance programs, copay cards, and disease-specific funds that may be able to help cover your medication costs.

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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Pfizer. Program terms may change — verify current requirements at [https://www.talzenna.com/support](https://www.talzenna.com/support) before applying.*

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Documents You'll Need

Proof of income (e.g., Tax returns, W2, or pay stubs)
Patient and Prescriber Enrollment Form
Prescription information

If You Don't Qualify for the Assistance Program

Manufacturer Savings Card (for insured patients)

Pfizer offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.

Common Questions

Most applications are processed within 2 to 3 business days after Pfizer receives all required documents, including your proof of income and the completed Patient and Prescriber Enrollment Form. Missing documents can delay the process, so make sure everything is submitted together.

If you are approved through Pfizer Oncology Together, your medication will be shipped directly to your home. You do not need to visit a pharmacy to pick it up.

Yes. Pfizer Oncology Together does accept Medicare patients who meet the financial eligibility criteria. Having Medicare does not automatically disqualify you from this program, which is different from some other manufacturer assistance programs.

Yes. Your enrollment in Pfizer Oncology Together must be renewed annually. Each year, you will need to resubmit updated income documentation and a new enrollment form to continue receiving Talzenna at no cost.

If your income exceeds the program threshold, you will likely not qualify for free medication through Pfizer Oncology Together. However, if you have commercial insurance, you may be eligible for the Talzenna savings card at https://www.talzenna.com/savings-and-support. You can also search for additional assistance at NeedyMeds.org or ask your care team about state pharmaceutical assistance programs.

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