Uptravi (selexipag)
Patient Assistance Program Guide — Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Must be uninsured, underinsured, or have Medicare Part D coverage with high out-of-pocket costs and meet specific eligibility criteria.
Residency
U.S. resident or resident of a U.S. territory with a valid address
Income Limits (500% FPL)
Threshold is calculated at 500% of FPL, which is standard for Janssen specialty pulmonary medications.
Based on 2025 HHS Federal Poverty Level guidelines.
# Getting Uptravi (Selexipag) Through the Johnson & Johnson Patient Assistance Foundation (JJPAF): A Complete Patient Guide
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Who Qualifies for the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF)?
If you have been prescribed Uptravi (selexipag) for pulmonary arterial hypertension and cannot afford the cost, you may qualify to receive it at no charge through the Johnson & Johnson Patient Assistance Foundation, Inc. (JJPAF). This program is designed specifically for patients who lack adequate insurance coverage or face high out-of-pocket costs. For a single-person household, the maximum annual income allowed is $75,300. To be eligible, you must be uninsured, underinsured, or have Medicare Part D coverage with costs that are difficult to manage. Meeting income and insurance requirements does not guarantee approval, but many patients who apply do qualify for free medication.
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About Uptravi (Selexipag)
Uptravi (selexipag) is an oral medication approved by the U.S. Food and Drug Administration (FDA) to treat pulmonary arterial hypertension (PAH), classified as WHO Group 1. It belongs to a class of drugs called IP receptor agonists, also known as prostacyclin receptor agonists, which work by targeting specific receptors involved in PAH. Uptravi is manufactured by Janssen, a Janssen Pharmaceutical company of Johnson & Johnson, in partnership with Actelion. As a specialty medication for a serious and complex condition, Uptravi carries a very high list price — often tens of thousands of dollars per year — making it unaffordable for many patients without insurance or financial assistance.
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Income Eligibility: Full Breakdown
JJPAF uses income thresholds set at 500% of the Federal Poverty Level (FPL), which is a standard benchmark used for Janssen specialty pulmonary medications. Your household size and total annual income both determine whether you qualify.
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
Income is typically verified using your most recent federal tax return, a W-2 form, or three months of recent pay stubs. If your income varies — for example, if you are self-employed or recently lost a job — the program may consider your current financial situation on a case-by-case basis. If your income is slightly above the limit for your household size, you may still want to apply, as larger household sizes allow for higher thresholds. If you do not qualify based on income, see the final section of this guide for alternative options that may still reduce your costs.
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Insurance Requirements Explained
Your insurance status plays an important role in whether you qualify for JJPAF. Here is how different situations are typically handled:
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Step-by-Step: How to Apply
Follow these steps to apply for Uptravi through JJPAF:
1. Gather your documents before you begin. You will need: a completed patient and prescriber section of the JJPAF application, proof of income (most recent tax return, W-2, or three months of pay stubs), and a copy of your Uptravi prescription.
2. Choose your application method. You can apply online, by phone, or by fax.
3. Apply online by visiting https://www.jjpaf.org. The online portal walks you through the application and allows you to upload supporting documents directly.
4. Apply by phone by calling (800) 652-6227. A program representative can assist you with the application and answer questions about eligibility.
5. Apply by fax by sending your completed application and documents to (888) 526-5168. Make sure all pages are legible and include your contact information on every page.
6. Have your prescriber complete their section. The application requires both patient and prescriber signatures. Coordinate with your doctor's office in advance to avoid delays.
7. Submit and wait for confirmation. After submission, keep a copy of everything you sent. You should receive a response within 2 to 10 business days.
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What to Expect: Timeline and Delivery
After you submit your application, processing typically takes 2 to 10 business days. You will be notified of your approval status by JJPAF or a program representative. If approved, your Uptravi will be shipped directly to your home address — you do not need to pick it up at a pharmacy or prescriber's office. No action is required at delivery beyond confirming receipt. Enrollment in the program is not permanent. You will need to reapply and reauthorize your enrollment once per year to continue receiving free medication. Mark your approval date on your calendar so you can prepare your renewal documents in advance.
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Alternatives If You Don't Qualify
If you do not meet the income or insurance requirements for JJPAF, there are still options that may help lower your cost for Uptravi or related treatments.
Biosimilar alternatives: Selexipag, the generic or biosimilar form of Uptravi, may be available at a lower cost. Ask your doctor whether this is a clinically appropriate option for you.
Manufacturer savings card: If you have commercial (private) insurance, you may qualify for cost savings through the JJwithMe savings program at https://www.jjwithme.com/uptravi/savings-and-support. This is separate from JJPAF and designed for insured patients.
State Pharmaceutical Assistance Programs (SPAPs): Many states offer programs that help residents pay for specialty medications. Your state health department or insurance commissioner's office can tell you what is available where you live.
NeedyMeds.org: This free online database at https://www.needymeds.org lists hundreds of patient assistance programs, coupons, and other cost-reduction resources that you may not find elsewhere.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Janssen (Actelion). Program terms may change — verify current requirements at [https://www.uptravi.com/support](https://www.uptravi.com/support) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Biosimilar / Generic Alternatives
FDA-approved alternatives to Uptravi: selexipag. Ask your prescriber if one of these is clinically appropriate for your condition.
Manufacturer Savings Card (for insured patients)
Janssen (Actelion) offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
Yes. Unlike many patient assistance programs, JJPAF does accept patients who have Medicare Part D coverage if you face high out-of-pocket costs and meet income and other eligibility requirements. You should apply and let the program evaluate your specific situation.
Processing typically takes 2 to 10 business days after JJPAF receives your completed application and all supporting documents. Once approved, your Uptravi is shipped directly to your home. Make sure your application is fully complete before submitting to avoid delays.
You will need a completed application with both the patient and prescriber sections filled out, proof of income such as your most recent tax return, W-2, or three months of pay stubs, and a copy of your Uptravi prescription. Having these ready before you start will speed up the process.
Yes. JJPAF requires annual reauthorization to continue receiving free Uptravi through the program. You will need to resubmit income documentation and have your prescriber re-sign the application. It is a good idea to start this process a few weeks before your current approval expires.
If your income is close to the limit, it is still worth applying. Household size affects the income threshold, so a larger household may qualify at a higher income level. If you are denied, ask the program about any appeals process or explore the alternative options listed in this guide, including state assistance programs and NeedyMeds.org.
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