Xolair (omalizumab)

Do You Qualify?

Income Limits (500% FPL)

Calculated based on 500% FPL for 2025; Genentech may adjust based on cost of living in specific areas or high medical expenses.

Based on 2025 HHS Federal Poverty Level guidelines.

# Getting Xolair (Omalizumab) at Low or No Cost Through the Genentech Patient Foundation

Who Qualifies for the Genentech Patient Foundation?

If you need Xolair and cannot afford it, the Genentech Patient Foundation may be able to provide it to you at little or no cost. This program is designed for patients who are uninsured, underinsured, or whose insurance does not cover Xolair. For a single-person household, the maximum annual income limit is $75,300. If you have Medicare, commercial insurance that falls short of covering your costs, or no insurance at all, you may still qualify — the program does not automatically exclude patients with government or private insurance. Income, insurance status, and a valid prescription are the three main factors the program reviews.

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About Xolair (Omalizumab)

Xolair (omalizumab) is a biologic medication — specifically an anti-IgE monoclonal antibody — manufactured by Genentech and Novartis. It is FDA-approved for moderate-to-severe persistent asthma, chronic spontaneous urticaria (CSU), nasal polyps, and IgE-mediated food allergy. Because Xolair is a biologic, it is produced from living cells and requires a complex manufacturing process. This makes it significantly more expensive than most traditional medications. Without insurance or financial assistance, the out-of-pocket cost can reach thousands of dollars per month, putting it out of reach for many patients who have been prescribed it.

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Income Eligibility: Full Breakdown

The Genentech Patient Foundation uses income thresholds based on approximately 500% of the Federal Poverty Level (FPL) for 2025. The table below shows the maximum annual income allowed by household size:

| Household Size | Maximum Annual Income |

|---|---|

| 1 person | $75,300 |

| 2 persons | $102,200 |

| 3 persons | $129,100 |

| 4 persons | $156,000 |

Income is typically verified using your most recent federal tax return, a W-2, or three months of recent pay stubs. If you are self-employed or have irregular income, alternative documentation may be accepted — contact the program directly to ask what they can accept.

If your income falls above these limits, you may not automatically be disqualified. Genentech notes that it may adjust eligibility based on the cost of living in your area or unusually high medical expenses. In other words, if you live in a high-cost region or face significant out-of-pocket healthcare costs, it is still worth applying or calling to discuss your situation. The income limits are a starting point, not always a hard cutoff.

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Insurance Requirements Explained

The Genentech Patient Foundation uses a flexible approach to insurance. Here is how different situations are typically handled:

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Step-by-Step: How to Apply

Follow these steps to apply for Xolair through the Genentech Patient Foundation:

1. Gather your documents before you start. You will need: a completed and signed application form, a current prescription for Xolair from your doctor, and proof of income (such as a federal tax return, W-2, or three months of recent pay stubs).

2. Choose your application method. You can apply online, by phone, or by fax.

- Online: Visit https://www.genentech-access.com/patient/brands/xolair.html and follow the application instructions on the page.

- By phone: Call (888) 941-3331 to speak with a program representative who can walk you through the process.

- By fax: Send your completed paperwork to (833) 943-2007.

3. Have your prescriber involved. Your doctor or their office staff will likely need to sign portions of the application and submit the prescription. Many providers are familiar with this process — ask your prescriber's office if they have a prior authorization or assistance coordinator.

4. Submit your application. Once all documents are complete and signed, submit through your chosen method.

5. Wait for review. The program typically completes its review within 2 business days.

6. Receive your approval notice. If approved, you will be notified with instructions on how to receive your medication.

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What to Expect: Timeline and Delivery

After submitting your application, the Genentech Patient Foundation typically completes its review within 2 business days. If approved, you will receive a confirmation, often through your prescriber's office or directly depending on how you applied. Xolair can be delivered either to your home or to your prescriber's office — the program supports both options. Because Xolair is typically administered by injection in a clinical setting, many patients have it sent to their doctor's office. You do not need to do anything special at pickup beyond your normal appointment. Approval through this program lasts one year. You will need to reauthorize annually, which means submitting updated income documentation and a renewed prescription each year to continue receiving assistance.

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Alternatives If You Don't Qualify

If you do not meet the Genentech Patient Foundation's requirements, you still have options:

1. Biosimilar alternatives: Xolair now has a biosimilar called Omlyclo (omalizumab-advi). Biosimilars are approved as highly similar to the original biologic and may be available at a lower cost. Ask your doctor if Omlyclo is appropriate for your situation.

2. Manufacturer savings card (insured patients): If you have commercial insurance, Genentech offers a co-pay savings card for Xolair that may reduce your out-of-pocket costs. You can find this program at https://www.xolair.com/financial-support/co-pay-card.html. Note that this card is generally not available to Medicare or Medicaid beneficiaries.

3. State Pharmaceutical Assistance Programs (SPAPs): Many states run their own drug assistance programs, especially for older adults or people with disabilities. Search your state's health department website or ask your local pharmacist for information.

4. NeedyMeds.org: This free, independent database lists hundreds of assistance programs by drug name or condition. It is a useful tool if you want to compare all available options in one place.

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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Genentech / Novartis. Program terms may change — verify current requirements at [https://www.genentech-access.com/patient/brands/xolair.html](https://www.genentech-access.com/patient/brands/xolair.html) before applying.*

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