Zeposia (ozanimod)
Patient Assistance Program Guide — Bristol Myers Squibb Patient Assistance Foundation (BMSPAF)
Do You Qualify?
Income
Up to $75,300 for a single person
Insurance
Must be uninsured or underinsured. Patients with Medicare Part D may qualify if they meet low-income requirements and have exhausted other options.
Residency
U.S. resident, Puerto Rico, or U.S. Virgin Islands
Income Limits (500% FPL)
Income threshold calculated at 500% of the 2025 Federal Poverty Level (FPL)
Based on 2025 HHS Federal Poverty Level guidelines.
# Free Zeposia (Ozanimod) Through the Bristol Myers Squibb Patient Assistance Foundation: A Complete Guide
Who Qualifies for the Bristol Myers Squibb Patient Assistance Foundation (BMSPAF)?
If you take Zeposia (ozanimod) for multiple sclerosis or ulcerative colitis and cannot afford it, you may be able to get it at no cost through the Bristol Myers Squibb Patient Assistance Foundation (BMSPAF). This program provides free Zeposia directly to patients who meet income and insurance requirements. For a single-person household, your annual income must be at or below $75,300 to qualify. On the insurance side, you generally must be uninsured or underinsured — meaning your current coverage does not adequately cover the cost of Zeposia. Some Medicare Part D enrollees may also qualify under specific conditions.
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About Zeposia (ozanimod)
Zeposia (ozanimod) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat relapsing forms of multiple sclerosis (RMS) and moderately to severely active ulcerative colitis (UC) in adults. It belongs to a drug class called sphingosine 1-phosphate (S1P) receptor modulators and is taken as an oral capsule. Without insurance or financial assistance, Zeposia carries a high list price that puts it out of reach for many patients. There are currently no FDA-approved generic or biosimilar versions of Zeposia available, which means the brand-name cost is the only option without a program like BMSPAF.
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Income Eligibility: Full Breakdown
The BMSPAF sets income limits at 500% of the 2025 Federal Poverty Level (FPL). The table below shows the maximum annual household income allowed by household size:
| Household Size | Maximum Annual Income |
|---|---|
| 1 person | $75,300 |
| 2 persons | $102,200 |
| 3 persons | $129,100 |
| 4 persons | $156,000 |
For households larger than four people, income thresholds continue to increase — contact BMSPAF directly at (800) 736-0003 to confirm the limit for your household size.
Income is typically verified using your most recent U.S. tax return, a W-2, or a 1099 form. If your income has recently changed, some programs accept three months of pay stubs as an alternative. It is worth applying even if you are close to the limit, since income from all household members — not just the patient — is generally counted together.
If your income is above these thresholds, you will likely not qualify for the free medication program. However, you may still have options. See the "Alternatives If You Don't Qualify" section below for other ways to reduce your costs.
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Insurance Requirements Explained
Your insurance situation plays a major role in whether you qualify. Here is how the program typically applies to different coverage types:
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Step-by-Step: How to Apply
Follow these steps to apply for free Zeposia through BMSPAF:
1. Gather your documents first. You will need: a valid Zeposia prescription from your doctor, proof of income (most recent U.S. tax return, W-2, or 1099), and a completed application form with both your signature and your prescriber's signature.
2. Choose your application method. You can apply online, by phone, or by fax.
- Online: Visit www.bmspaf.org to complete and submit your application digitally.
- Phone: Call (800) 736-0003 to apply with assistance from a program representative. Representatives can also answer eligibility questions before you apply.
- Fax: Submit your completed application and documents by fax to (888) 776-2370.
3. Have your prescriber complete their section. The application requires your doctor's signature and prescriber information. Coordinate this ahead of time to avoid delays.
4. Submit all documents together. Incomplete applications take longer to process. Make sure your income documentation, prescription, and signed application are all included.
5. Wait for confirmation. After submission, BMSPAF will review your application. Processing typically takes 5 to 7 business days.
6. Receive approval notice. If approved, you will be notified and your medication will be arranged for delivery.
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What to Expect: Timeline and Delivery
Once you submit a complete application, BMSPAF typically processes it within 5 to 7 business days. You will receive confirmation of approval, after which your Zeposia will be shipped directly to your home address — you do not need to pick it up from a pharmacy or your doctor's office. No action is required from you at the point of delivery beyond being available to receive the shipment.
Your enrollment in the program is not permanent. Annual reauthorization is required, meaning you will need to reapply and reconfirm your eligibility each year. Watch for renewal notices from BMSPAF as your annual approval period approaches to avoid a gap in your medication supply.
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Alternatives If You Don't Qualify
If BMSPAF determines you are not eligible, here are other options to explore:
1. Biosimilars: There are currently no FDA-approved biosimilar or generic versions of Zeposia (ozanimod) available. This option does not apply at this time.
2. Zeposia Savings Card (for insured patients): If you have commercial insurance, Bristol Myers Squibb offers a savings card that may reduce your out-of-pocket costs. Visit www.zeposia.com/savings-support to check eligibility and enroll. This option is typically not available to Medicare or Medicaid enrollees.
3. State Pharmaceutical Assistance Programs (SPAPs): Many states run their own programs to help residents afford prescription medications. Eligibility and benefits vary widely by state. Search for your state's program through your state health department website.
4. NeedyMeds.org: This free, independent database lists hundreds of patient assistance programs, copay cards, and disease-specific funds. Visit www.needymeds.org to search by drug name or condition. It costs nothing to use and is updated regularly.
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*This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Bristol Myers Squibb. Program terms may change — verify current requirements at [https://www.bms.com/patient-and-caregiver-support/patient-assistance-foundation.html](https://www.bms.com/patient-and-caregiver-support/patient-assistance-foundation.html) before applying.*
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Documents You'll Need
If You Don't Qualify for the Assistance Program
Manufacturer Savings Card (for insured patients)
Bristol Myers Squibb offers a savings card that may reduce your out-of-pocket cost if you have commercial insurance. Ask your prescriber or pharmacist for current savings card details.
Common Questions
BMSPAF typically processes complete applications within 5 to 7 business days. Once approved, your Zeposia will be shipped directly to your home. Incomplete applications — missing a signature, income document, or prescription — can cause delays, so make sure everything is included before you submit.
Possibly. Medicare Part D patients are generally not eligible for manufacturer assistance programs under federal rules, but BMSPAF may make exceptions for patients who meet low-income requirements and have exhausted other options. Call BMSPAF at (800) 736-0003 to discuss your specific situation before assuming you do not qualify.
Yes. BMSPAF requires annual reauthorization to confirm that you still meet income and insurance eligibility requirements. You will need to submit updated income documentation and a renewed prescription each year. It is a good idea to start the renewal process early to avoid any gap in receiving your medication.
If your income exceeds the program threshold, you will most likely not qualify for free medication through BMSPAF. However, if you have private insurance, you may be eligible for the Zeposia savings card at www.zeposia.com/savings-support. You can also search NeedyMeds.org or contact your state pharmaceutical assistance program for other options.
No. As of now, there are no FDA-approved generic or biosimilar versions of Zeposia (ozanimod) available in the United States. This means the brand-name medication is currently the only form of ozanimod on the market, which makes patient assistance programs like BMSPAF especially important for patients who cannot afford the full cost.
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